Concentration of Surfactant in Microemulsions as Novel Drug Delivery Systems

Abstract

Microemulsions are clear, stable, isotropic thermodynamically stable systems mixtures of oil, water and ,surfactant frequently in combination with a cosurfactant. Microemulsion system has acceptable potential to act as a drug delivery vehicle by putting a wide range of drug molecules. It has most effective advantage like excellent thermodynamic stability, high drug solubilization capacity, improved oral bioavailability and protection against enzymatic hydrolysis. Surfactant based chemical systems have been reported in many studies and their technological implementations are potential facts in enhanced oil recovery activities. Three different microemulsions – oil external, water external and middle phase can be used for drug delivery, depending upon the type of drug delivery upon the type of drug and the site of action. This paper reviews the role of different types of surfactants in enhanced oil recovery & effect on the phase behavior, physico-chemical properties and drug release.

Keywords: Cosurfactants, Microemulsions, NDDS, Solubilization, Surfactant, Thermodynamics

Cite this Article

Ambika Nand Jha, Jignesh S. Patel. Concentration of Surfactant in Microemulsions as Novel Drug Delivery Systems. Research & Reviews: A Journal of Drug Formulation, Development and Production. 2020; 7(2): 8–15p.