A Review on Treatments of Gout for Future Aspects

Abstract

Gout is the most common inflammatory arthritis in adults, and is caused by excess uric acid pools in the body, which leads to the formation of monosodium urate (MSU) crystals and their deposition in and around joints where they induce inflammation, leading to acute gout attacks. The extreme inflammatory burden and pain of an acute gout attack can be unbearable. The prevalence of gout appears to be increasing and may affect up to 8 million people in the United States and this disease mainly occurs in men aged more than 50, affecting approximately 1–2% of adult men in the western world. The development of novel therapies for gout after 40 years has opened new understanding of this disease. A study from Vellore revealed that 15.8% of the affected patients are less than 30 years. The quality of care for many patients with gout is unfortunately not in keeping with current guidelines. Rather than providing a comprehensive overview of gout, this review focuses on various classes of drugs used in the treatment of gout such as short-term and long treatments with allopathic medicines and alternative medicines.

Keywords: Gout, monosodium urate crystals, allopathic medicines, alternative medicines

Cite this Article Manpreet Singh, Kaushik Madan L. A Review on Treatments of Gout for Future Aspects. Research and Reviews: A Journal of Pharmaceutical Science. 2017; 8(3):    1–6p.