Medicinal Chemistry of Nanoparticles for Cancer Theranostics

Abstract

Cancer is a disease in which cells growth is uncontrollable and conventional treatment have a few side effects, for example, nonspecific delivery, unable to enter the center of tumor and absence of solubility. Nanoparticles could directly target disease cells specifically and increased medication localization in tumor cells giving exact cellular uptake. The theranostic nanomedicine can accomplish systemic flow, avoid host resistances and deliver the medication and diagnostic agents at the target site to analyze and treat the tumor at cellular and molecular level; in short it is a combination of therapeutic and diagnostic agent. Gold nanoparticles, quantum dots are used as nanotheranostics. These agents act by passive and active targeting on cancerous cells. Synthesis of nanotheranostic is also discussed.

Keywords: Cancer, Nanotheranostics, Quantum dots, Gold nanoparticle

Cite this Article

Sandip Zine, Sarita Kunchikorve, Pooja Dubey. Medicinal Chemistry of Nanoparticles for Cancer Theranostics. Research & Reviews: A Journal of Drug Design & Discovery. 2016; 3(3):       28–41p.