Laxative Activity of Root of Moringa pterygosperma

Authors

  • M. K. Kambale Department of Pharmacology, Appasaheb Birnale College of Pharmacy, South Shivaji Nagar, Sangli-416416, India
  • M. Kumawat Department of Pharmacology, Appasaheb Birnale College of Pharmacy, South Shivaji Nagar, Sangli-416416, India
  • N. S. Naikwade Department of Pharmacology, Appasaheb Birnale College of Pharmacy, South Shivaji Nagar, Sangli-416416, India
  • D. D. Chougule Department of Pharmacology, Appasaheb Birnale College of Pharmacy, South Shivaji Nagar, Sangli-416416, India

Abstract

 

Crude aqueous extract of root of Moringa pterygosperma (family: Moringaceae) at dose 100 and 200 mg/kg was investigated for laxative activity according to Cappaso et al. in albino rats that were compared with standard drug agar-agar (300 mg/kg, p.o.) in normal saline. The rats were fasted for 12 h before the experiment. After 8 h of drug administration, the faeces were collected and weighed. The extract was found to produce significant laxative activity in dose-dependant manner. The activity may be contributed to the phytoconstituents present.

 

Keywords: Moringa pterygosperma, laxative activity, faeces, agar-agar

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Published

2021-01-09

Issue

Vol. 2 No. 2 (2012)

Section

Review Article

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