Development, Characterization and Evaluation of Topical Gel of Clove Oil

Authors

  • Megha Sharma Department of Pharmacy, Shri Ram Institute of Technology, Near ITI, Madhotal, Jabalpur-482002 (M. P.), India
  • Khushboo Nechlan Department of Pharmacy, Shri Ram Institute of Technology, Near ITI, Madhotal, Jabalpur-482002 (M. P.), India
  • Seema Kohli K. N. Polytechnic, Department of Pharmacy, Jabalpur (M. P.), India

Abstract

 

A wide choice of vehicles ranging from solid to semisolid forms has been used for skin care and of dermatological disease. High molecular-weight water-soluble polymers of sodium carboxymethyl cellulose (CMC), gelatin, sodium alginate that possess very high viscosity, transparency, film forming properties at low concentration, are reported to be useful in formation of gel. In the present research work, gels of clove oil using different gel-forming agents such as sodium CMC, sodium alginate, gelatin, and gum tragacanth were prepared with an objective to increase transparency and spreadability. The prepared gels were characterized for pH, spreadability, consistency, homogenecity, skin irritation, and drug content and stability studies. Results show that gel made of sodium CMC has good consistency, homogenecity, spreadability, stability and has wider prospect for topical preparations as compared to sodium alginate, gelatin, tragacanth gum, and PVA gel containing clove oil.

 

Keywords: Clove oil, sodium CMC, gelatin, sodium alginate

Downloads

Published

2021-01-11

Issue

Vol. 2 No. 3 (2012)

Section

Research Article

License

Declaration and Copyright Transfer Form

(to be completed by authors)

I/ We, the undersigned author(s) of the submitted manuscript, hereby declare, that the above manuscript which is submitted for publication in the STM Journals(s), is not published already in part or whole (except in the form of abstract) in any journal or magazine for private or public circulation, and, is not under consideration of publication elsewhere.

  • I/We will not withdraw the manuscript after 1 week of submission as I have read the Author Guidelines and will adhere to the guidelines.
  • I/We Author(s ) have niether given nor will give this manuscript elsewhere for publishing after submitting in STM Journal(s).
  • I/ We have read the original version of the manuscript and am/ are responsible for the thought contents embodied in it. The work dealt in the manuscript is my/ our own, and my/ our individual contribution to this work is significant enough to qualify for authorship.
  •  I/We also agree to the authorship of the article in the following order:

Author’s name                                    

 

1. ________________

2. ________________

3. ________________

4. ________________

 

We  Author(s) tick this box and would request you to consider it as our signature as we agree to the terms of this Copyright Notice, which will apply to this submission if and when it is published by this journal.