Pharmacognostical overview of Gymnema sylvestre and its role in the manifestation of metabolic syndrome and other diseases: a review
Abstract
Keywords
Full Text:
PDFReferences
Ramasubramania R, Sekar M, Pallavi JV, Pramoda K, Poojitha P, Lakshmi DS. Gymnema sylvestre-an overview. World J Pharm Res. 2007; 6: 191–195. doi: 10.20959/wjpr201710-9267.
Farzana K, Mokuleswar SM, Long CM, Isa NM, Chao Z, Bassem Y et al. Comprehensive review on phytochemicals, pharmacological and clinical potentials of Gymnema sylvestre. Front Pharmacol. 2019; 29. doi: 10.3389%2Ffphar.2019.01223.
Sastry BS; Gymnema sylvestre. Varanasi, India: Bhav Prakash Nighantu Chaukhambha; 1994.
Ahmed SK, Cheekavolu C, Alasyam N, Sunil M. Evaluation of hypoglycemic property of gurmar (Gymnema sylvestre) leaves methanolic extract (GSLME) in streptozocin (STZ) induced diabetic albino rats. J Med Sci Clin Res. 2017; 5 (12): 31753–31760. doi: 10.18535/jmscr/v5i12.78.
Devangan S, Varghese B, Johny E, Gurram S, Adela R. The effect of Gymnema sylvestre supplementation on glycemic control in type 2 diabetes patients: A systematic review and meta-analysis. Phytother Res. 2021; 35 (12): 6802–6812. doi: 10.1002/ptr.7265. PMID 34467577.
Laha S, Santanu P. Gymnema sylvestre (Gurmar): a potent herb with anti-diabetic and antioxidant potential. Pharmacogn J. 2019; 11 (2): 201–206. doi: 10.5530/pj.2019.11.33.
Gaytán Martínez LA, Sánchez-Ruiz LA, Zuñiga LY, González-Ortiz M, Martínez-Abundis E. Effect of Gymnema sylvestre administration on glycemic control, insulin secretion, and insulin sensitivity in patients with impaired glucose tolerance. J Med Food. 2021; 24 (1): 28–32. doi: 10.1089/jmf.2020.0024. PMID 32460589.
Arora DS, Sood H. In vitro antimicrobial potential of extracts and phytoconstituents from Gymnema sylvestre R.Br. leaves and their biosafety evaluation. AMB Express. 2017; 7 (1): 115. doi: 10.1186/s13568-017-0416-z, PMID 28587443.
Kang MH, Lee MS, Choi MK, Min KS, Shibamoto T. Hypoglycemic activity of Gymnemasylvestre extracts on oxidative stress and antioxidant status in diabetic rats. J Agric Food Chem. 2012; 60 (10): 2517–2524. doi: 10.1021/jf205086b, PMID 22360666.
Kahksha AO, Alam O, Naaz S, Sharma V, Manaithiya A, Khan J et al. Recent developments made in the assessment of the antidiabetic potential of Gymnema species: from 2016 to 2020. J Ethnopharmacol. 2022; 286: 114908. doi: 10.1016/j.jep.2021.114908. PMID 34906636.
Mani JS, Johnson JB, Hosking H, Ashwath N, Walsh KB, Neilsen PM et al. Antioxidative and therapeutic potential of selected Australian plants: a review. J Ethnopharmacol. 2021; 268: 113580. doi: 10.1016/j.jep.2020.113580. PMID 33189842.
Ankit S, Chetan S, Aneja KR, Rakesh P, Sylvestre G. (Gurmar): a review. Pharm Lett. 2010; 2: 275–284.
Surendra KM, Astalakshmi N, Arshida PT, Deepthi K, Nidhin DM, Shafna PM et al. A concise review on gurmar-gymnema sylvestre. World J Pharm Pharm Sci. 2015; 4 (10): 430–448.
Pragya T, Mishra BN, Neelam SS. Phytochemical and pharmacological properties of Gymnema sylvestre: an important medicinal plant. BioMed Res Int. 2014; 1. doi: 10.1155/2014/830285. 15.Qiu Q, Zhen HS, Huang PQ. Study on volatile components from flowers of Gymnema sylvestre. Zhong Yao Cai. 2013; 36 (4): 575–577. PMID 24134005.
Potawale SE, Shinde VM, Anandi L, Borade DH, Deshmukh RS, Sylvestre G. A comprehensive review. Pharmacologyonline. 2008; 2: 144–157.
Joy PP, Thomas J. Medicinal plants. Kerala agriculture university, aromatic and medicinal plants research station. Med Aromat Plants. 1998; 16. doi: 10.4172/2167-0412.1000278.
Zhen HS, Zhu XY, Lu RM, Liang J, Qiu Q, Meng QM. Research on chemical constituents from stem of Gymnemasylvestre. Zhong Yao Cai. 2008; 31 (8): 1154–1156. PMID 19112892.
Jamadagni PS, Pawar SD, Jamadagni SB, Gautam M, Gaidhani SN, G P Prasad P et al. Recent updates in research on Gymnema sylvestre. Pharmacogn Rev. 2021; 15 (30): 128–133. doi: 10.5530/phrev.2021.15.15.
Dewangan HK, Singh N, Kumar Megh SK, Singh S, Lakshmi. Optimisation and evaluation of Gymnema sylvestre extract loaded polymeric nanoparticles for enhancement of in vivo efficacy and reduction of toxicity. J Microencapsul. 2022; 39 (2): 125–135. doi: 10.1080/02652048.2022.2051625, PMID 35282781.
Jain KS, Kathiravan MK, Somani RS, Shishoo CJ. The biology and chemistry of hyperlipidemia. Bioorg Med Chem. 2007; 15 (14): 4674–4699. doi: 10.1016/j.bmc.2007.04.031, PMID 17521912.
Khanna V, Kannabiran K. Anticancer-cytotoxic activity of saponins isolated from the leaves of Gymnemasylvestre and Eclipta prostrata on HeLa cells. Int J Green Pharm. 2009; 3: 227–229. doi: 10.22377/ijgp.v10i04.
Malik JK, Manvi FV, Nanjware BR, Dwivedi DK, Purohit P, Chouhan S. Antiarthritic activity of leaves of Gymnemasylvestre R. Br. leaves in rats. Pharm Lett. 2010; 336–341:2010, 2.
Kiranmai M, Kazim SM, Ibrahim M. Combined wound healing activity of Gymnema sylvestre and Tagetes erecta linn. Int J Pharm Appl. 2011; 2: 135–140.
Kirtikar KR, Basu BD. Indian medicinal plants. 1975: 3. doi: 10.1076/phbi.37.3.237.6296.
Warrier PK, Nambiar VPK, Ramankutty C. Indian medicinal plants: a compendium of 500 Species. 1st ed. Vol. 3. Hyderabad, India: Orient Longman; 1994.
Liu M, Zhou T, Zhang J, Liao G, Lu R, Yang X. Identification of C21 steroidal glycosides from Gymnema sylvestre (Retz.) and evaluation of their glucose uptake activities. Molecules. 2021; 26 (21): 6549. doi: 10.3390/molecules26216549, PMID 34770958, PMCID PMC8588469.
Ounjaijean S, Sukati S, Somsak V, Sarakul O. The potential role of Gymnema inodorum leaf extract treatment in hematological parameters in mice infected with Plasmodium berghei. J Trop Med. 2021; 2021: 9989862. doi: 10.1155/2021/9989862, PMID 34257672, PMCID PMC8260294.
Sugihara Y, Nojima H, Marsuda H, Murakami M, Yoshikawa T, Kimura I. Antihyperglycemic effects of gymnemic acid IV, a compound derived from Gymnemasylvestre leaves in streptozotocin-diabetic mice. J Asian Nat Prod Res. 2000; 2: 321–327. doi: 10.1080/10286020.2019.1593968.
Anis M, Sharma MP, Iqbal M. Herbal ethnomedicine of the Gwalior Forest division in Madhya Pradesh, India. Pharm Biol. 2000; 38 (4): 241–253. doi: 10.1076/1388-0209(200009)3841-AFT241.
Preuss HG, Bagchi D, Bagchi M, Rao CV, Dey DK, Satyanarayana S. Effects of a natural extract of (-)-hydroxycitric acid (HCA-SX) and a combination of HCA-SX plus niacin-bound chromium and Gymnema sylvestre extract on weight loss. Diabetes Obes Metab. 2004; 6 (3): 171–180. doi: 10.1111/j.1462-8902.2004.00328.x. PMID 15056124. 32.Asbaghi O, Ashtary-Larky D, Bagheri R, Moosavian SP, Olyaei HP, Nazarian B et al. Folic acid supplementation improves glycemic control for diabetes prevention and management: a systematic review and dose-response meta-analysis of randomized controlled trials. Nutrients. 2021;13 (7): 2355. doi: 10.3390/nu13072355, PMID 34371867, PMCID PMC8308657.
Devangan S, Varghese B, Johny E, Gurram S, Adela Ramu. The effect of Gymnema sylvestre supplementation on glycemic control in type 2 diabetes patients: a systematic review and meta-analysis. Phytother Res. 2021; 35 (12): 6802–6812. doi: 10.1002/ptr.7265, PMID 34467577.
Bhalerao PD, Vikhe S. Woody climbing shrub: gymnema sylvestre: a review. World J Pharm Med Res. 2022; 8 (5): 103–107.
Saumendu DR, Sarkar K, Dipankar S, Singh T, Prabha B. In vitro antibiotic activity of various extracts of Gymnemasylvestre. Int J Pharm Res Dev. 2010; 2: 1–3. doi: 10.1039/C8NP00092A.
Pitchai D, James E, Khanzan A, Majeed MF. A novel dihydroxy Gymnemic triacetate isolated from Gymnema sylvestre possessing normoglycemic and hypolipidemic activity on STZ induced diabetic rats. J Ethnopharmacol. 2009; 126: 339–344. doi: 10.1016/j.jep.2019.112374.
Merrily AK, Winston D. Herbal therapy and supplements: a scientific and traditional approach. Philadelphia, PA: Lippincott Williams & Wilkins; 2000.
Shenoy R, Kumar DJ, Hg N, Manonmani HK. In silico evaluation of naturally isolated triterpene glycosides (TG) from Gymnema sylvestre towards diabetic treatment. Heliyon. 2021; 7 (12). doi: 10.1016/j.heliyon.2021.e08407.
Gurav S, Gulkari V, Duragkar N, Patil A. Systemic review: pharmacognosy, phytochemistry, pharmacology and clinical applications of Gymnema sylvestre. Pharmacogn Rev. 2007; 1 (2): 338–343.
DOI: https://doi.org/10.37591/rrjopc.v10i1.1279
Refbacks
- There are currently no refbacks.
Copyright (c) 2023 Research & Reviews A Journal of Pharmacognosy