Preparation of Oral Gels Containing Ethanolic Extract of anacardiumoccidentale L and Characterization

Abstract

The anti-microbial activity of gel containing Anacardiumoccidentale L. leaf extract was investigated. A total of four formulations (ST1–ST4) and a control (without leaf extract) were prepared. All the formulations were evaluated for physical appearance and physical properties of gel like pH, viscosity, spreadability and extrudability. The results of all the physical parameters of the gel were found to be within the limits. All the four formulations including control were evaluated for anti-microbial activity against Porphyromonas gingivalis and Prevotella intermedia by cup plate method. The zone of inhibition developed in the plate was measured for antimicrobial activity. Among the four formulations ST3 showed zone of inhibition similar to that of the standard, hence the gel of Anacardiumoccidentale L. leaf extract showed promising anti-microbial activity against the microorganism used in the study.

Keywords: Anacardiumoccidentale L, anti-microbial activity, Porphyromonas gingivalis, Prevotella intermedia

Cite this Article

Narayana Charyulu R, Prashant Nayak, Sofia Sunny et al. Preparation of Oral Gels Containing Ethanolic Extract of anacardiumoccidentaleL and Characterization. Research & Reviews: A Journal of Pharmacognosy. 2015; 2(3): 16–20p.