Flash Chromtography and Its Analytical Application: A Review
Abstract
Different chromatography techniques such as TLC, HPTLC, HPLC etc. are mainly used for separation of mixture. The column chromatography was use in many laboratories for separation and purification of different components. The separation of components based on partitioning or adsorption of solute on stationary to purify the liquids and for reaction control in organic synthesis.Column chromatography is a time consuming process. Flash Chromatography is a development of novel preparative liquid chromatography in which mobile phase flows down by positive air pressure. It is a rapid form of preparative column chromatography based on an air pressure driven hybrid of medium and short column chromatography optimized for rapid separation of organic compound. It is a simple, fast, economic and flexible process.
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Still WC, Kahn M, Mitra A. Rapid chromatographic technique for preparative separations with moderate resolution.J.Org.Chem.1978:43(14):2923–2925.
Roge A, Firke S, Kawde R, Sarje S, vadavalkar S. Breif review on flash chromatography. International journal of Pharmaceutical science & Research, 2011; 2(8);1930 1937.
Ayare P*, Khanvilkar V, Chalak N. Flash chromatography: Area and application. Pharmatutor, 2014; 2(5); 89–103.
William C. S, Hill D. C. General methods for flash chromatography using disposable column. Mol. Divers, 2009; 13(2); 247–252.
SkoogDA, Holler FJ, Crouch SR. Fundamental of Instrumental Analysis. India: Thomson Books/Cole Publication, 2007.
Bhusal R, Nahar D, Dalvi P. Review on Flash column chromatography, Indo American Journal of Pharmaceutical Research, 2017;7(01); 7353–7358.
Chaudhari H, Chaudhari F, Patel M, Pradhan P, Upadhyay U. Review on Flash Chromatography, International Journal of Pharmaceutical Development & Technology,2012; 2(2);80–84.
Dewick P, John Wiley & Sons, Inc., Hoboken, Medicinal natural products; a biosynthetic approach, New Jersey, 2009.
Discoveryscience.com
Buchi. Preparative Chromatography Solutions. Available online at: https://www.buchi.com/in-en/content/preparative-chromatography-solutions
Technical Bulletin.Input TLC Rf values. Available online at: http://yamazenusa.com/images/technical_bulletin_No44.pdf
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