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Comparative study of Polyherbal anti-diabetic syrup with the Marketed formulation
Abstract
Diabetes, is commonly referred to as diabetes mellitus, it’s a group of metabolic disorder in which the person has high blood glucose (blood sugar), either due to insufficient insulin secretion or the body cells not responding to insulin. Polyuria (frequent urination) and polydipsia (growing thirst and hunger) are common in patients with high blood sugar (polyphagia). This present study reveals that comparative study of poly herbal anti-diabetic syrup with marketed formulation. Evaluation parameters like colour, odour, taste, pH, viscosity, specific gravity, density are compared with a marketed formulation. Tri-herbal and single herbal formulations were less effective than polyherbal formulations, which were rich in alkaloids, tanins, and terpenoids.
References
Bakare, R.I., Magbagbeola, O.A., Okunowo O.W., 2010. Nutritional and chemical evaluation of Momordica charantia. J.Med Plant. Res.2010;4(21): 2189-2193.
Barnabas, B.B., Mann, A., Ogunrinola, T.S., P.E., Screening for Anthelminthic activities from extracts of zanthoxyloides, Neocarya and Celosia laxa against ascaris infection in rabbits. Int. J. App. Res. Nat. Prod. 2010;3(4): 1-4.
Bhattacharya, S., Das, B. 2012. Anti-diabetic activity of Lagenaria siceraria pulp and seed extract in normal and alloxan induced diabetic rats. Int. J. Pharm. Sci. Res.2012; 3(9): 3362-3369.
Deshpande, S.V., In vitro antioxidant study of petroleum ether chloroform and ethyl acetate fractions of Coccinia grandis stems extract. Int. J. Chem. Sci. (2011); 9(1): 80-86.
Dhiman, K., Gupta, A., Sharma, D.K., Gill, N.S., A. Review on the medicinally important plants of the family Cucurbitaceae. Asian. J. Clin.Nutri.2012; 4(1): 16-26.
Doss, A., Dhanabalan, R. Antihyperglycemic and insulin release effects of Coccinia grandis (L.) voigt leaves in normal and alloxan diabetic rat. Ethnobot. Leaflets.2008; 12: 1172-1175.
Fernandes, N.P., Lagishetty, C.V., Panda, V.S., S.R. An experimental evaluation of the antidiabetic and properties of a standardized Momordica charantia fruit extract. BMC Complement. Alter. Med.2007; 7: 29.
Grover, J.K., Vats, V., Rathi, S. effects of Eugenia and Tinosporacordifolia inexperimental diabetes and their effects on key metabolic enzymes involved in carbohydrate metabolism. J.2000;73(3): 461-470.
Indian Council of Medical Research Task Force.2012. Assessment of effects on health due to consumption of bitter bottle gourd (Lagenaria siceraria) juice. Indian J. Med. Res.2012; 135: 49-55.
Ivan, A.R. Medicinal Plants of the World.2nd ed. Humana Press, New York, 83, W., Wiwat, C., Vongsakul, M., A., Leelamanit, Suwannaroj, N., Ebizuka, Y.,2001. HIV inhibitor from Thai bitter gourd. Planta. Medica.2003; 67(4): 350-353.
Joseph, B., Jini, D. 2013. Antidiabetic effects of momodica charantia (bitter melon) and its medicinal potency. Asian. Pac. J.Trop. Dis. 2013;3(2): 93-102.
Kamalakannan, N., Prince, P.S.M. Antihyperglycemic and antioxidant effect of rutin, a polyphenolic flavonoid, in streptozotocin induced diabetic wistar rats. Basic. Clin. Pharmacol. Toxicol.2006;98(1): 97-103.
Ko, B.S., Choi, S.B., Park, S.K., Jang, J.S., Kim, Y.E., Park, S., 2005. Insulin sensitizin and insulinotropic action of berberine from Cortidis rhizoma. Biol. Pharm.Bull. 2005; 28(8): 1431-1437.
Kocyan, A., Zhang, L.B., Schaefer, H., Renner, S.S., A multi-locus chloroplast phylogeny for the Cucurbitaceae and its implications for character evolution and classification. Mol. Phylogenet. Evol.2007; 44(2): 553-557.
Leng, S.H., Lu, F.E., Xu, L.J. 2004. Therapeutic effects of berberine in impaired glucose tolerance rats and its influence on insulin secretion. Acta. Pharmaceutica. Sinica. B. 2004; 25(4): 496-502.
Leung, L., Birtwhistle, R., Kotecha. J., Hannah, S., Cuthbertson, S. 2009. Anti-diabetic and hypoglycaemic effects of Momordica charantia (bitter melon): A mini review. British J. Nutr. 2009;102(12): 1703-1708.
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