Comparison Study of the Reactivity of 2-Acetyl Heterocyclic Compound toward Aldol Condensation with Benzaldehyde Derivatives

Abstract

Some new chalcones have been synthesized by condensation of 2-acetyl pyrrol, 3-acetyl pyridine and 3-acetyl indole with various aromatic aldehydes in 25% alcoholic alkali. The synthesized compounds were identified by spectral and physical methods. From the time of reactions and the yield of the products, we can state that there were some obvious differences in the reactivity between the heterocyclic compounds used.

Keywords: Reactivity, chalcone, aldol condensation, heterocyclic compounds, benzaldehyde

Cite this Article
Khlafulla Abdulrahim M, Al Mohamad F. Comparison Study of the Reactivity of 2-Acetyl Heterocyclic Compound toward Aldol Condensation with Benzaldehyde Derivatives. Research and Reviews: A Journal of Pharmaceutical Science. 2016; 7(1):
34–38p.