Polycystic Ovary syndrome: A disorder of alarming proportion

Abstract

Polycystic Ovary Syndrome is one of the most important endocrine disorders that affects women of the reproductive age and may cause serious complications. Insulin resistance plays a key role in the pathophysiology of this syndrome, and this makes the use of oral anti-diabetic drugs most compelling. The majority of studies have shown amelioration of typical symptoms such as hyperandrogenism and cycle irregularities following the use of oral anti-diabetics, and ovulation and pregnancy rates increased. The reproductive and metabolic features of PCOS are sometimes reversible with lifestyle modifications such as weight loss and exercise. Further research is needed to find the exact etiology, methods of prevention and proper management of this endocrine disorder. Though, a plethora of treatment options have arrived for PCOS in recent years the lifestyle modification including a structured meal plan and exercise schedule remains the cornerstone and the most effective modality of treatment till date. As a general rule all other treatment options are added to this depending upon the gravity of the presenting problems. PCOS has achieved an alarming proportion. In this review, we will briefly describe about this multifaceted disorder.

Keywords: Polycystic ovary syndrome, insulin resistance, Metformin, exercise, weight reduction.

Cite this Article

Irfat Ara, Maqsood Mohd, Mudasir Maqbool, Tawseef Ahmad Hajam. Polycystic Ovary syndrome: A disorder of alarming proportion. Research & Reviews: A Journal Pharmaceutical Science. 2020; 11(2): 1–7p.