Open Access Open Access  Restricted Access Subscription or Fee Access

Formulation and Development of Iguratimod Film Coated Tablets 25 mg

Rekha Kandukuri, Mekkanti Manasa Rekha, Rinku Mathappan, C. Pavithra, R. Aruna

Abstract


Iguratamide is chemically called as methanesulfonanilid for the treatment of rheumatoid arthritis. The present invention relates to the micron zing technology for insoluble polycrystal medicine Iguratimod, and the micronized Iguratimod has new crystallization and powder direct compression method for formulating tablets. The orally taken quick release preparation with micronized Iguratimod as active component, high efficiency super disintegrants like cross carmellose sodium, surfactants like sodium lauryl sulphate, diluents like MCC PH 102, Lactose DC GRADE etc. have obviously improved in vitro leaching rate and in vivo absorption rate, and obviously raised bioavailability.

 

Keywords: Iguratimod, Lactose DC Grade, Mannitol DC Grade, sodium lauryl sulphate, cross carmellose sodium, hydroxy propyl cellulose, Povidone K-30 and Opadry white

 

Cite this Article

Rekha Kandukuri, Mekkanti Manasa Rekha, Rinku Mathappan, C. Pavithra, R. Aruna. Formulation and Development of Iguratimod Film Coated Tablets 25 mg. Trends in Drug Delivery. 2020; 7(1): 25–31p.


Full Text:

PDF

Refbacks

  • There are currently no refbacks.


Copyright (c) 2020 Trends in Drug Delivery