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Isolation, Characterization of Rhinacanthus Nasutus L. Kurz and Its Biological Evaluation

P. Jaya Preethi, K. Bindu Sree, A. Sirisha, Pavan Kumar, S. Ruby, T. Sivakumar



The present paper deals with isolation, characterization and evaluation of anti-inflammatory, analgesic and anti-bacterial activities of n-hexane extract of Rhinacanthus nasutus L. Kurz. Extraction was carried out with soxhlet apparatus using solvents of increasing polarity. The anti-inflammatory activity was done by Carrageenan-Induced Paw Edema in rats. Analgesic activity was done by hot plate method and anti-bacterial activity by plate hole diffusion method. n-Hexane extract exhibited significant change in anti-inflammatory, analgesic activities when compared with the standard drug and control. Antibacterial screening of n-hexane extract was 100% active in concentration of 1000 µg/ml, 93% active in concentration of 500 µg/ml, and 87.5% active in concentration of 250 µg/ml.


 Keywords: rhinacanthus nasuta (L) kurz, phytochemical screening, anti-inflammatory, 

analgesic, anti-bacterial.

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