A comparative study of the Therapeutic Stratergies used in the treatment of Covid-19

Abstract

In late December 2019, an outbreak of an emerging disease (COVID-19) due to a novel coronavirus (later named SARS-CoV-2) started in Wuhan, China and rapidly spread in China and outside  The WHO declared the epidemic of COVID-19 as a pandemic on March 12^th 2020 . According to a recent Chinese study, about 80% of patients present with mild disease and the overall case-fatality rate is about 2.3% but reaches 8.0% in patients aged 70 to 79 years and 14.8% in those aged ≥80 years . Numerous preventative strategies and non-pharmaceutical interventions have been employed to mitigate the spread of disease including careful infection control, the isolation of patients, and social distancing. Management is predominantly focused on the provision of supportive care, with oxygen therapy representing the major treatment intervention. Medical therapy involving corticosteroids and antivirals have also been encouraged as part of critical management schemes. However, there is at present no specific antiviral recommended for the treatment of COVID-1.