Isolation, Characterization of Rhinacanthus Nasutus L. Kurz and Its Biological Evaluation

Authors

  • P. Jaya Preethi Department of Pharmacy, Nandha College of Pharmacy and Research Institute, Koorapalayam Piruvu, Erode, Tamil Nadu, India
  • K. Bindu Sree Department of Pharmacy, Nandha College of Pharmacy and Research Institute, Koorapalayam Piruvu, Erode, Tamil Nadu, India
  • A. Sirisha Department of Pharmacy, Nandha College of Pharmacy and Research Institute, Koorapalayam Piruvu, Erode, Tamil Nadu, India
  • Pavan Kumar Department of Pharmacy, Nandha College of Pharmacy and Research Institute, Koorapalayam Piruvu, Erode, Tamil Nadu, India
  • S. Ruby Department of Pharmacy, Nandha College of Pharmacy and Research Institute, Koorapalayam Piruvu, Erode, Tamil Nadu, India
  • T. Sivakumar Department of Pharmacy, Nandha College of Pharmacy and Research Institute, Koorapalayam Piruvu, Erode, Tamil Nadu, India

Abstract

 

The present paper deals with isolation, characterization and evaluation of anti-inflammatory, analgesic and anti-bacterial activities of n-hexane extract of Rhinacanthus nasutus L. Kurz. Extraction was carried out with soxhlet apparatus using solvents of increasing polarity. The anti-inflammatory activity was done by Carrageenan-Induced Paw Edema in rats. Analgesic activity was done by hot plate method and anti-bacterial activity by plate hole diffusion method. n-Hexane extract exhibited significant change in anti-inflammatory, analgesic activities when compared with the standard drug and control. Antibacterial screening of n-hexane extract was 100% active in concentration of 1000 µg/ml, 93% active in concentration of 500 µg/ml, and 87.5% active in concentration of 250 µg/ml.

 

 Keywords: rhinacanthus nasuta (L) kurz, phytochemical screening, anti-inflammatory, 

analgesic, anti-bacterial.

Downloads

Published

2021-01-07

Issue

Vol. 3 No. 1 (2013)

Section

Research Article

License

Declaration and Copyright Transfer Form

(to be completed by authors)

I/ We, the undersigned author(s) of the submitted manuscript, hereby declare, that the above manuscript which is submitted for publication in the STM Journals(s), is not published already in part or whole (except in the form of abstract) in any journal or magazine for private or public circulation, and, is not under consideration of publication elsewhere.

  • I/We will not withdraw the manuscript after 1 week of submission as I have read the Author Guidelines and will adhere to the guidelines.
  • I/We Author(s ) have niether given nor will give this manuscript elsewhere for publishing after submitting in STM Journal(s).
  • I/ We have read the original version of the manuscript and am/ are responsible for the thought contents embodied in it. The work dealt in the manuscript is my/ our own, and my/ our individual contribution to this work is significant enough to qualify for authorship.
  •  I/We also agree to the authorship of the article in the following order:

Author’s name                                    

 

1. ________________

2. ________________

3. ________________

4. ________________

 

We  Author(s) tick this box and would request you to consider it as our signature as we agree to the terms of this Copyright Notice, which will apply to this submission if and when it is published by this journal.