Chemical Constituents and Antacid Activity of Aqueous Extract of the Leaves of Sanchezia nobilis Hook.f. from Vietnam
Abstract
From the aqueous extract of the leaves of Sanchezia nobilis Hook.f. collected in Nam Dinh province by chromatographic methods. Their chemical structures were elucidated by the measurements of melting temperature, rotation angle, mass spectrometry (MS), nuclear magnetic resonance (NMR) and compared with previously published data. These were identified as: 4',5,7-trihydroxy-3',5'-dimethoxyflavone (NX1), kaempferol-3-O-α-L-arabinofuranoside (NX2), kaempferol-3-O-β-D-glucopyranoside (NX3). These all compounds were isolated from the leaves of Sanchezia nobilis for the first time. Evaluation the antacid activity of the n-hexane, ethylacetate and water fractions from the extract of this plant showed that the antacid effect of water fraction was better than the other two fractions, but the underlying trend remained weaker than that of antacid Antigas.
Keywords: Sanchezia nobilis Hook.f, 4',5,7-trihydroxy-3',5'-dimethoxyflavone, kaempferol-3-O-α-L-arabinofuranoside, kaempferol-3-O-β-D-glucopyranoside.
Cite this Article
Loi Vu Duc, Xuan Bui Thi, Ngoc Tran Minh. Chemical Constituents and Antacid Activity of Aqueous Extract of the Leaves of Sanchezia nobilis Hook.f. from Vietnam. Research & Reviews: A Journal of Pharmacognosy. 2019; 6(2): 15–22p.
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E.C. & Smith Leonard, L.B. (1964), "Sanchezia and related American Acanthaceae.", Rhodora 66, pp. 313-343
Ho Pham Hoang (2000), Viet Nam Vegetation, Young publisher, pp 39.
Mohammadjavad Paydar et al (2013), "In vitro anti-oxidant and anti-cancer activity of methanolic extract from Sanchezia speciosa leaves", Pakistan Journal of Biological Sciences. 16(20), pp. 1212-1215.
Shumaia Parvin. Abu Shuaib Rafshanjani., Md Abdul Kader., et al (2014), "In vitro antibacterial, antifungal and insecticidal activities of ethanolic extract and its fractionates of Sanchezia speciosa Hook. f", Int Res J Pharm 5(9), pp. 717-720
Nusrat Shaheen, Muhammad Uzair, Bashir Ahmad Ch and Alamgeer (2017); “In vitro cytotoxicity of Sanchezia speciosa extracts on human epithelial cervical cancer (hela) cell line”; Acta Poloniae Pharmaceutica - Drug Research, pp: 1389-1394
Ahmed E. Abd Ellah, Khaled M. Mohamed, Enaam Y. Backheet, and Mahmoud H. Mohamed1 (2014), “Cinnamyl alcohol, benzyl alcohol and flavonoid glycosides from Sanchezia nobilis”, Chemistry of Natural Compounds; pp 823-826
J. C. Omondi Seline Omondi (2015), "Phytochemical analysis of 50 selected plants found in the University Botanic Garden, Maseno, Kenya for their chemotaxonomic values", Journal of Medicinal Herbs and Ethnomedicine, Vol 1, pp. 130-135.
Mohamed K.M Ellah A.E.A, Backheet E.Y, et al (2013), "Matsutake alcohol glycosides from Sanchezia nobilis" Chemistry of Natural Compuonds, pp 930-933
Hans Gerhard, (2008) Drug discovery and evaluation, phamacological assays, Spinger- verlag Berlin Heidelberg New York, 3rd Edition, pp 1220-1221
Ministry of Health (2018), Vietnam Phamacopoea, 5rd Edition, Medicine publisher, Hanoi, pp. 454-455
Gyies K. (2005), “Gastric mucosal protection from prostaglandin to Gene- therapy”, Current Medicinal Chemistry 12, pp. 209- 215. 131
Chuihua Kong, X.X., Bin Zhou, Fei Hu, Chaoxian Zhang, Maoxian Zhang (2004), “Two compounds from allelopathic rice accession and their inhibitory activity on weeds and fungal pathogens”, Phytochemistry, 65: pp. 1123-1128.
Hyoung Ja Kim, Eun-R’’ Woo and Hokoon Park (1994), “A novel lignan and flavonoid from Polygonum aviculare”, Journal of Naturd Products, 5, pp. 581-586
Ziyin Yang, Y.T., Susanne Baldermann, Fang Dong, Yi Xu, Naoharu Watanabe (2009), “Isolation and identification of compounds from the ethanolic extract of flowers of the tea (Camellia sinensis) plant and their contribution to the antioxidant capacity”, Food Science and Technology, 42: pp 1439–1443.
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