Open Access Open Access  Restricted Access Subscription or Fee Access

Ethanolic Extract of Hemigraphis Colorata Leaves: Extraction, Phytochemical Screening, and in Vitro Evaluation of Antiulcer Activity

M. Sushma, S. Lahari, B. Jayanthi

Abstract


This study aims to extract the phytochemical constituents and in-vitro evaluation of   antiulcer activity of Hemigraphis colorata (Acanthaceae) Commonly known as red flameivy, belongs to the family Acanthaceae. Used to advance pee, checkhemorrhage, stopdysentery, treat veneral sicknesses and to recuperate hemorrhoids. Preliminary phytochemical screening revealed the presence of the leaves contain flavonoids, polyphenols, tannins, high potassium and low sodium levels; stem contains saponins and tannins, roots contain flavonoids and polyphenols. This study has taken with the antiulcer activity and preliminary phytochemical screening on the Hemigraphis colorata. In the present study, qualitative study of    the phytochemicals present in the sample was determined, antiulcer were carried out. On the premise of the prevailing study, the outcomes eventually concluded that the ethanolic extract of Hemigraphis colorata own antiulcer pastime. This evaluation offers an concept that the compound of the plant Hemigraphis colorata may be used as lead compound for designing other diseases.

 


Keywords


Hemigraphis colorata, Phyto-chemical screening, antiulcer activity, hemigraphis alternate, Acanthaceae

Full Text:

PDF

References


Davidson-Hunt I. Ecological ethnobotany: stumbling toward new practices and paradigms. MASA J. 2000;16(1):1–13.

Liu Y, Dao Z, Liu Y, Long C. Medicinal plants used by the Tibetan in Shangri-la, Yannan, China. Ethnobiol. Ethnomed. 2009 May 5; 5:15.

Kebriaee-zadeh A. Overview of national drug policy of Iran. Iranian J. Pharm. Res. 2003; 2:1–2. 4.

Gledhill D. The Names of Plants. 3rd Edn. Ann Bot. 2003 Feb; 91(3): 404.

Gamble JS. Flora of the Presidency of Madras. The Authority of the secretary of state of Indian council, India 1921; 2:1344.

Anonymous. The Glossary of Indian Medicinal Plants. Council of Scientific and Industrial Research, New Delhi, India, 1986, 224.

Anonymous. Dictionary of Indian Medicinal Plants. Central Institute of Medicinal and Aromatic Plants, Lucknow, India, 1992, 416.

Narasimhan SNY. Medicinal Plants of India. Vol. I, Karnataka, India, 1997, 73

Silja VP, Varma KS, Mohanan KV. Ethnomedicinal plant knowledge of the Mullu Kuruma tribe of Wayanad district, Kerala. Ind J Tradit Knowl 2008; 7:604-612.

Gayathri V, Lekshmi P, Padmanabhan RN. Anti-Diabetes and Hypoglycaemic properties of Hemigraphis colorata in Rats. Int J Pharm Pharm Sci 2012; 4(2):224-328.

Bourdy G, Walter A. Maternity and medicinal plants in Vanuatu I. The cycle of reproduction. J Ethnopharmacol 1992; 37(3):179-196.

Subramoniam A, Evans DA, Rajasekharan S, Nair GS. Effect of Hemigraphis colorata (Blume) H.G. Hallier leaf on wound healing and inflammation in Mice. Ind J Pharmacol 2001; 33:283-285.

Saravanan J, Shariff WR, Joshi NH, Varatharajan R, Joshi VG, Karigar AA. Preliminary Pharmacognostical and Phytochemical Studies of Leaves of Hemigraphis colorata. Research Journal of Pharmacognosy and Phytochemistry. 2010; 2(1):15-7.

Sheu J, Jayakumar T, Chang C, ChenY, Priya S, Ong E, Chiou H, Elizebeth AR. Pharmacological actions of an ethanolic extracts of the leaves Hemigraphis colorata and Clerodendron phlomoides. Clinical Molecular Medicine 2012; 3:1-3.

Akhil TT and Prabhu P: Evaluation of anti-oxidant, anti-inflammatory and cytotoxicity potential of Hemigraphis colorata. Int J Pharm Sci Res 2013: 4(9); 3477-3483.

Bhowmik D, Chiranjib TK, Pankaj KS. Recent trends of treatment and medication peptic ulcerative disorder. Int J Pharm Tech Research. 2010;2(1):970-80.

Vyawahare N, Deshmukh V, Gadkari M, Kagathara V. Plants with antiulcer activity. Pharmacognosy Reviews. 2009;3(5):118.

Wormsley KG. Aetiology of ulcers. Bailliere's clinical gastroenterology. 1988 Jul 1;2(3):555-71.

Scanlon VC, Sanders T. Essentials of anatomy and physiology. F.A. Davis Company; 6th edition (6 October 2010).

Tripathi KD. Essentials of pharmacology. New Delhi, Jaypee brother’s medical publishers Pvt. Ltd.1999. 2004;256.

Prabha P, Karpagam T, Varalakshmi B, Packiavathy AS. Indigenous anti-ulcer activity of Musa sapientum on peptic ulcer. Pharmacognosy research. 2011 Oct;3(4):232.

Mehta D. Ulcer-review on types, anti-ulcer drugs, anti-ulcer medicinal plants, anti-ulcer drug market, diagnostics and current global clinical trials status. Invent Rapid Pharm Pract. 2016; 2:1-8.




DOI: https://doi.org/10.37591/(rrjops).v13i1.1168

Refbacks

  • There are currently no refbacks.


Copyright (c) 2022 Research and Reviews: A Journal of Pharmaceutical Science