In vitro Quality Control Testing: A comparative Study of Jan Aushadhi with Different Brands of Metformin Tablets Available in India

Authors

  • Nirav R Panchal Maliba Pharmacy College, Gopal Vidyanagar, Bardoli Mahuva Road, TARSADI Surat Gujarat, India
  • Pratik M Tailor Assistant Professor Maliba Pharmacy College, Gopal Vidyanagar, Bardoli Mahuva Road, TARSADI Surat Gujarat, India
  • Ashish D Mishra Professor Maliba Pharmacy College, Gopal Vidyanagar, Bardoli Mahuva Road, TARSADI Surat Gujarat, India
  • Shailesh A Shah Professor Maliba Pharmacy College, Gopal Vidyanagar, Bardoli Mahuva Road, TARSADI Surat Gujarat, India

DOI:

https://doi.org/10.37591/(rrjops).v10i2.501

Abstract

Metformin hydrochloride is an oral anti-diabetic drug used mainly to treat type-II Diabetes Mellitus and it is widely available in different brands in the market, making it challenging to select the safe, effective and economic one. The endeavour of this experiment was to compare and assess the quality standard of the Jan Aushadhi medicine with a different brand of the metformin hydrochloride tablet available in India. For evaluation of the quality of tablet of different brands, Indian Pharmacopoeial parameters like weight variation, dissolution tests and drug assay were executed. The results of all these parameters of different brands were compared with the pharmacopoeial limits.

 

Keywords: Metformin hydrochloride, Dissolution, Weight variation, Drug Assay

Cite this Article

Nirav Panchal, Pratik Tailor, Ashish Mishra, Shailesh Shah. In vitro Quality Control Testing: A Comparative Study of Jan Aushadhi with Different Brands of Metformin Tablets Available in India. Research & Reviews: A Journal of Pharmaceutical Science. 2019; 10(2):
32–37p.

Published

2019-08-26

Issue

Section

Research Article