Characterization of Tabletting Properties of Mango Gum

Authors

  • Mudit Dixit Department of Pharmaceutics, NGSM Institute of Pharmaceutical Sciences, Nitte University, Mangalore, Karnataka, India
  • Selvam P. R.
  • Kulkarni P. K.
  • Charyulu R. N.

DOI:

https://doi.org/10.37591/rrjodfdp.v1i2.314

Abstract

The aim of the study is to elucidate the physical, thermal, sorption, and functional properties of a mango gum obtained from the stem of Mangifera indica were characterized viz. elemental analysis, Fourier transmittance infrared, particle size analysis, thermogravimetric analysis, differential scanning colorimetry, scanning electron microscopy, and X-ray powder diffraction. Mango gum had a glass transition temperature (Tg) and melting peak of 90 and 318.795°C, respectively. This material showed a 14.59% loss in weight at 200°C. The sample had peaks at approximately 21°, 29°, and 39° 2θ degrees of 2-theta (θ) in the X-ray powder diffraction pattern. Elemental analysis showed that mango gum contains 35.62, 6.12, 56.57, and 1.67% of carbon, hydrogen, oxygen, and nitrogen, respectively. The results obtained in this study establish the fundamental characteristics of mango gum. The in vitro drug release was found to be 95.07% at 30 min ketoprofen tablets with 2.5% w/w binder concentration showed optimum results than standard binder, thus conclusion was drawn that mango gum was found to be useful for the preparation of uncoated tablet dosage form.

 

Keywords: Mangifera indica, mango gum, tablet binder, excipients, ketoprofe

Downloads

Published

2019-03-19

Issue

Vol. 1 No. 2 (2014)

Section

Research Article

License

Declaration and Copyright Transfer Form

(to be completed by authors)

I/ We, the undersigned author(s) of the submitted manuscript, hereby declare, that the above manuscript which is submitted for publication in the STM Journals(s), is not published already in part or whole (except in the form of abstract) in any journal or magazine for private or public circulation, and, is not under consideration of publication elsewhere.

  • I/We will not withdraw the manuscript after 1 week of submission as I have read the Author Guidelines and will adhere to the guidelines.
  • I/We Author(s ) have niether given nor will give this manuscript elsewhere for publishing after submitting in STM Journal(s).
  • I/ We have read the original version of the manuscript and am/ are responsible for the thought contents embodied in it. The work dealt in the manuscript is my/ our own, and my/ our individual contribution to this work is significant enough to qualify for authorship.
  •  I/We also agree to the authorship of the article in the following order:

Author’s name                                    

 

1. ________________

2. ________________

3. ________________

4. ________________

 

We  Author(s) tick this box and would request you to consider it as our signature as we agree to the terms of this Copyright Notice, which will apply to this submission if and when it is published by this journal.